Effects of pentoxifylline on oxidative stress in rats with abdominal compartment syndrome model


Egin S., Açıksarı K. , Ercan G., Aydin A. F. , Ustyol E. A. , Eser M., ...Daha Fazla

INTERNATIONAL JOURNAL OF SURGERY OPEN, cilt.5, ss.5-10, 2016 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.ijso.2016.09.001
  • Dergi Adı: INTERNATIONAL JOURNAL OF SURGERY OPEN
  • Sayfa Sayıları: ss.5-10

Özet

Background: Abdominal compartment syndrome (ACS) causes severe pathology in the cardiovascular, renal and pulmonary systems. Recent studies showed that pentoxifylline (PTX) has effects on increasing tissue oxygenation, healing capillary refill and reducing superoxides and hydroxyl radicals by inhibiting xanthine oxidase. In this study, our aim was to study the effects of PTX on free oxygen radicals and oxidative damage in rats with ACS model.