Laparoscopic Compared with Open D2 Gastrectomy on Perioperative and Long-Term, Stage-Stratified Oncological Outcomes for Gastric Cancer: A Propensity Score-Matched Analysis of the IMIGASTRIC Database


Trastulli S., Desiderio J., Lin J., Reim D., Zheng C., Borghi F., ...More

CANCERS, vol.13, no.18, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 18
  • Publication Date: 2021
  • Doi Number: 10.3390/cancers13184526
  • Title of Journal : CANCERS
  • Keywords: gastric cancer, laparoscopy, minimally invasive surgery, LYMPH-NODE DISSECTION, ASSISTED DISTAL GASTRECTOMY, RADICAL GASTRECTOMY, LYMPHADENECTOMY, SURVIVAL, COMPLICATIONS, FEASIBILITY, CARCINOMA

Abstract

Simple Summary:Gastric resection with D2 lymphadenectomy is considered the gold standard for the treatment of both advanced and early gastric cancer with lymph node metastasis. The performance of D2 lymphadenectomy is technically challenging and represents a key factor in improving patients' survival. For these reasons, the execution of gastrectomy with D2 lymphadenectomy using the traditional open surgical technique still represents the most widespread approach and, based on current international guidelines, the indication for laparoscopic surgery is limited to early gastric cancer that does not require a D2 lymphadenectomy. The present study aimed to investigate the use of laparoscopic versus open surgical approaches in performing gastrectomy with D2 lymphadenectomy for cancer in terms of intraoperative and postoperative outcomes and long-term survival. The study was conducted using the data collected in the International study group on Minimally Invasive surgery for Gastric Cancer (IMIGASTRIC) international database.