COMPARISON OF INTERFERON-GAMMA RELEASE ASSAY VERSUS TUBERCULIN SKIN TEST FOR LATENT TUBERCULOSIS SCREENING IN HEMODIALYSIS PATIENTS


Ates G., Ozekinci T. , Yildiz T., Danis R.

BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, cilt.23, ss.1242-1246, 2009 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 23 Konu: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1080/13102818.2009.10817646
  • Dergi Adı: BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
  • Sayfa Sayısı: ss.1242-1246

Özet

Early diagnosis and proper treatment of latent tuberculosis infection (LTB1) in patients with end stage renal diseases (ESRD) is critical to reduce increased reactivation risk of LTB1. However; this condition is known to decrease responsiveness to the tubercidin skin test (TST). A new, diagnostic test [QuantiFERON-TB Gold in-tube (QFT-GIT)] has been developed using mycobacterium tuberculosis specific antigens for the identification of LTB1. We aimed to evaluate the two test methods among hemodialysis patients for their diagnostic usefulness.