Extracellular matrix protein 1 gene rs3737240 single nucleotide polymorphism is associated with ulcerative colitis in Turkish patients


Adalı G., ERSOY TUNALI N. , Yorulmaz E., Tiryakioğlu N., Mungan S. G. , Ulaşoğlu C., et al.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.28, ss.254-259, 2017

  • Cilt numarası: 28 Konu: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/tjg.2017.17043
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Sayfa Sayısı: ss.254-259

Özet

Background/Aims: Ulcerative colitis (UC) and Crohn's disease are chronic inflammatory diseases. Genetic, immunologic, and microbial factors play an important role in their pathogenesis. Extracellular matrix protein 1 (ECM1), a gene related to mucosal barrier function, has been shown to be associated with UC. This study aims to determine the relationship between ECM1 gene rs3737240 single nucleotide polymorphism (SNP) and UC in a group of Turkish patients.