JOURNAL OF SURGICAL RESEARCH, vol.267, pp.63-70, 2021 (Peer-Reviewed Journal)
Article / Article
JOURNAL OF SURGICAL RESEARCH
Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
Lycopene, Mesenteric ischemia, Intestinal ischemia reperfusion, Immunoglobulin A, Bacterial translocation, Intestinal barrier, SPINAL-CORD-INJURY, RETINOIC ACID, RATS, INNATE, DAMAGE, DYSFUNCTION, BARRIER
Background: Intestinal ischemia causes an inflammatory response that may become intense by reperfusion and result in bacterial translocation. Intestinal immunoglobulin A is known to be a barrier against bacterial translocation. Lycopene is a compound with antioxidant and anti-inflammatory properties. We hypothesized that lycopene has positive effects in ischemia-reperfusion of the intestine through the intestinal IgA.