Effects of whole-body chronic microwave exposure on some hormones of variously treated rats

Akdag M., Sert C., Kaya H., Dasdag S., Celik M.

BIOCHEMICAL ARCHIVES, vol.15, no.4, pp.345-350, 1999 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 1999
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.345-350


To investigate the effects of chronic whole-body microwave exposure, on serum Thyroid Stimulating Hormone (TSH), thyroxin (T-4), triiodothyronine (T-3), Cortisol, Growth Hormone (GH), Follicular Stimulating Hormone (FSH) and Estradiol concentrations, Wistar-albino female rats without treated and treated Vitamin C and Vitamin E were exposed to Microwave (MW) with a frequency of 9.450 MHz at the power density of 2.65 mW/cm(2) with corresponding specific absorption rate of 1.80 W/kg for 1h/day during 21 days. Vitamin C (150 mg/kg/day) and Vitamin E (150 mg/kg/day) were administrated during last seven exposure days to MW+Vit.C (n=8) and MW+Vit.E (n=8) groups respectively. Rectal temperatures were measured in all female rats. Serum levels of GH and FSH decreased (p<0.05, p<0.01 respectively) while estradiol levels increased in MW exposure group (p<0.05). But other hormones did not change in MW group (n=8). All hormone levels of rats treated with Vitamin C did not change (p>0.05). T-3 and T-4 hormones of exposed rats were found to be significant at MW +Vit.E group according to MW group (p<0.05). Rectal temperature differences were found to be significant in experimental groups according to sham group (n=8) (p<0.05). It was concluded that the changes of hormone concentrations under study was consistent with MW-induced thermal stimulation of Hypothalamic-Hypophysial-Adrenal (HHA) and Hypothalamic-Hypophysial-Thyroid (HHT) activity and Vitamin E might play role in changing T-3 and T-4 hormones.