Anxiety Caused by Traumatic Brain Injury Correlates to Decreased Prefrontal Cortex VEGF Immunoreactivity and Neuron Density in Immature Rats

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Baykara B., Cetin F. , Baykara B., Aksu I., Dayi A., Kiray M., ...More

TURKISH NEUROSURGERY, vol.22, no.5, pp.604-610, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2012
  • Doi Number: 10.5137/1019-5149.jtn.5633-11.1
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.604-610


AIM: Traumatic brain injury (TBI) may cause neuropsychiatric disorders such as anxiety disorder which has negative effects on cognitive functions and behavior. The aim of this study is to investigate the effects of TBI on anxiety and vascular endothelial growth factor (VEGF) immunoreactivity on the prefrontal cortex of immature rats, which is one of the anxiety-related regions of the brain in 7-day-old immature rats subjected to contusion injury.