The Role of a Single Nucleotide Polymorphism of the Matrix Metalloproteinase-1 Gene Promoter Region in Invasion and Prognosis of Meningiomas


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EFENDIOGLU M., BASARAN R., Bayrak O. F. , ISIK N., Kaner T., Sahin F., et al.

TURKISH NEUROSURGERY, cilt.24, ss.731-736, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5137/1019-5149.jtn.9823-13.1
  • Dergi Adı: TURKISH NEUROSURGERY
  • Sayfa Sayısı: ss.731-736

Özet

AIM:The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region in meningiomas and its effect on invasion and prognosis.