IL-36a and IL-36y expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study

Erdem O., Leblebici C., Aksu A. E. K. , Erdil D., Polat A. K. , Gürel M. S.

JOURNAL OF CUTANEOUS PATHOLOGY, 2021 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2021
  • Doi Number: 10.1111/cup.14105
  • Journal Name: JOURNAL OF CUTANEOUS PATHOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: IL-36a, IL-36y, immunohistochemistry, palmoplantar eczema, palmoplantar psoriasis, ALLERGIC CONTACT-DERMATITIS, HAND ECZEMA, IL-36-GAMMA, CYTOKINES, IL-1F9

Abstract

Background: Diagnosing hyperkeratotic lesions on the palms and soles is often challenging for both clinicians and pathologists. Interleukin (IL)-36 cytokines play an important role in the pathogenesis of psoriasis.