Effects of hemostatic polysaccharide agent on epidural fibrosis formation after lumbar laminectomy in rats


SPINE JOURNAL, vol.16, no.3, pp.414-419, 2016 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.spinee.2015.11.014
  • Title of Journal : SPINE JOURNAL
  • Page Numbers: pp.414-419


BACKGROUND CONTEXT: Epidural fibrosis is a common adverse outcome of spinal surgery that can compress the dural sac and nerve root. Local hemostatic agents have many indications in numerous types of spinal surgery. As these agents may behave as foreign bodies, inducing inflammation and delaying regeneration, they could enhance the risk of epidural fibrosis.