Effects of hemostatic polysaccharide agent on epidural fibrosis formation after lumbar laminectomy in rats


USLU S.

SPINE JOURNAL, vol.16, no.3, pp.414-419, 2016 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.spinee.2015.11.014
  • Journal Name: SPINE JOURNAL
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.414-419

Abstract

BACKGROUND CONTEXT: Epidural fibrosis is a common adverse outcome of spinal surgery that can compress the dural sac and nerve root. Local hemostatic agents have many indications in numerous types of spinal surgery. As these agents may behave as foreign bodies, inducing inflammation and delaying regeneration, they could enhance the risk of epidural fibrosis.