Alpha-Fetoprotein-Producing Gastric Cancer with Nonbiliary Pancreatitis

YAVUZ A., Guelec B., Girgin R. B. , Tuncer I.

CASE REPORTS IN GASTROENTEROLOGY, vol.15, no.1, pp.80-86, 2021 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 15 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1159/000511294
  • Journal Indexes: Emerging Sources Citation Index, Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
  • Page Numbers: pp.80-86
  • Keywords: Pancreatitis, Alpha-fetoprotein, Metastasis, Gastric cancer, METASTATIC TUMORS, EXPRESSION, ADENOCARCINOMA, CARCINOMA, RESECTION, PROTEIN, LIVER


Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC) is a rare, aggressive tumor. In the absence of metastasis in diagnosis, close observation and long-term follow-up is needed to monitor and slow its progress. We report a young patient who presented with nonbiliary pancreatitis. Upon finding Virchow's nodule, we conducted tests and observed multiple lymph nodes and liver and pancreatic metastasis. We subsequently made a diagnosis of AFPGC. This study describes the different presentations of this rare but aggressive subtype of gastric cancer with a review of the literature. (C) 2021 The Author(s) Published by S. Karger AG, Basel