TLR4 Gene Polymorphism in Patients with Nonalcoholic Fatty Liver Disease in Comparison to Healthy Controls

Kızıltas S., Kızıltas S., Ata P., Çolak Y., Mesci B., Şenateş E., ...More

METABOLIC SYNDROME AND RELATED DISORDERS, vol.12, no.3, pp.165-170, 2014 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1089/met.2013.0120
  • Journal Name: METABOLIC SYNDROME AND RELATED DISORDERS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.165-170

Abstract

Objectives: Recent studies have suggested that bacterial overgrowth and endotoxemia along with its receptor, Toll-like receptor 4 (TLR-4), play a role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The present study was designed to test and evaluate the TLR4 gene polymorphism in patients with NAFLD in comparison to healthy controls.