Adrenomedullin and total nitrite levels in children with familial Mediterranean fever


Balat A., Islek I., Cekmen M. B. , Yurekli M., Tekin D., Muslu A., et al.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, cilt.42, ss.240-243, 2006 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 42 Konu: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1440-1754.2006.00845.x
  • Dergi Adı: JOURNAL OF PAEDIATRICS AND CHILD HEALTH
  • Sayfa Sayısı: ss.240-243

Özet

Aim: Familial Mediterranean fever (FMF) is the most frequent periodic syndrome characterised by recurrent attacks of polyserositis. However, recent studies revealed that there might be an ongoing subclinical inflammation between the attacks. As nitric oxide (NO) and adrenomedullin (AM) are both synthesised in the endothelium, and mediates many functions within immune system, we considered them to be an interesting target of investigation in FMF.