Palaces are cultural heritage sites that have survived from the past to the present day as symbols of a nation's individual culture and civilization. The Ottoman Palaces which can be currently accessed reflect the architectural and aesthetic conception as well as the palace structure, annexation and gardens of the palace complexes of the period. For this reason, they should be protected as a priority as examples of unique cultural heritage. Some sections of these palaces built on the Bosphorus and in urban areas have survived to the present day, while some of the buildings and outbuildings could not be accessed due to damage from fires and earthquakes or expropriation works. As a result, the originality and integrity of the palace complex and its collections have also been distorted. Protection methods such as light, temperature, relative humidity, dust, vibration, air pollution, microbiological activity, and safety controls should be applied in the scope of preventive protection within the framework of national and international conservation principles. Preventive protection is an important contribution to the achievements in safeguarding historical heritage sites, to extend their life into future generations and the formation of cultural memory. The main purpose of museum palaces is to protect the collections stored within not only for a long time, but also safely. Therefore, museum protection strategies should aim for long-term protection. Many projects and scientific activities are being carried out in order to provide preventive protection conditions in indoor and outdoor sections of museum palaces in Europe. With these projects, national and international platforms are being established to eliminate risk factors that are detrimental to museum palace structures. In addition, periodic training on preservation methods should be given to directors and staff of museum palace collections. Destructive disasters such as fire, which can cause serious negative consequences, may occur naturally or may be attributable to human error and flaws. Risk assessment and emergency planning studies therefore have great importance faced with these destructive effects. Emergency procedures and plans should be developed by many stakeholder institutions as a matter of urgency. The aim of this work is to ensure the creation of a professional and detailed "risk management application" for potential risks in museum palaces. The establishment of a risk identification team and the documentation of all risks by this team would ensure that these risks are discussed and set up on the basis of prior or existing damage and deterioration. The scope of the work extends to museum managers, conservation professionals (restorers and conservators), occupational health and safety professionals and information professionals. The determination of the most appropriate and up-to-date risk management techniques by monitoring all the risk parameters will also prevent budget, labor and time losses. These efforts should be made to establish fast decision making mechanisms for effective risk management and emergency management strategies to increase the fortification of museum palaces against all risks.