MAY DOXYCYCLINE-RIFAMPICIN COMBINATION BE THE FIRST-LINE THERAPY FOR OSTEOARTICULAR BRUCELLOSIS?


Hocaoglu S., Mesci E.

ACTA MEDICA MEDITERRANEA, vol.30, no.1, pp.255-260, 2014 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2014
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.255-260
  • Keywords: Brucellosis, doxycycline, rheumatic disease, rifampicin, spondylitis, sacroiliitis, DIFFERENT AGE-GROUPS, INVOLVEMENT, COMPLICATIONS, SPONDYLITIS, METAANALYSIS, ANATOLIA

Abstract

Aims: Brucellosis is an infectious disease which can mimic rheumatoid diseases due to its osteoarticular (OA) involvements. Treatment failure and recurrences have not been completely eliminated yet in patients with OA brucellosis. This study aimed to investigate rheumatologic manifestations observed in patients with OA brucellosis and the outcomes of combination therapy with doxycycline and rifampicin (DR) in such patients.