Uric acid as a potential mediator of cardiovascular morbidity in obstructive sleep apnea syndrome

KANBAY, ASİYE; Inonu, Handan; Solak, Yalcin; Erden, Abdulsamet; Uslu, Emine; Yuksel, Sevgi; Ozturk, Mehmet; McFann, Kim; Johnson, Richard; Kanbay, MEHMET

doi:10.1016/j.ejim.2014.04.005

Uric acid as a potential mediator of cardiovascular morbidity in obstructive sleep apnea syndrome

KANBAY A. , Inonu H., Solak Y., Erden A., Uslu E., Yuksel S. A. , ...More

EUROPEAN JOURNAL OF INTERNAL MEDICINE, vol.25, no.5, pp.471-476, 2014 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 25 Issue: 5
Publication Date: 2014
Doi Number: 10.1016/j.ejim.2014.04.005
Title of Journal : EUROPEAN JOURNAL OF INTERNAL MEDICINE
Page Numbers: pp.471-476

Abstract

Background and aims: Obstructive sleep apnea (OSA) is now considered as an independent risk factor for cardiovascular (CV) disease. Although uric acid is increasingly being implicated in CV morbidity and mortality, no study attempted to determine independent role of uric acid in CV morbidity of OSA patients. We aimed to assess the role of serum uric acid as a potential mechanism of CV morbidity in a nonselected cohort of OSA patients.