Chondroid syringoma (CS) is an uncommon, benign mixed tumor of the skin, composed of mesenchymal and sweat gland elements. In this report, we present a rare case of CS in the middle finger of a 53-year-old male patient. Excisional biopsy and skin grafting were performed. At 2 years of follow-up, the patient had no recurrence. Timely diagnosis and wide excision with a broad margin should be the preferred treatment. Pathologists and clinicians should be aware of the malignant component of CS. (C) 2021 SFCM. Published by Elsevier Masson SAS. All rights reserved.