Coronary flow reserve is impaired in patients with slow coronary flow


Erdogan D., ÇALIŞKAN M. , Güllü H., Sezgin A. T. , Yıldırır A., Müderrisoglu İ. H.

ATHEROSCLEROSIS, vol.191, no.1, pp.168-174, 2007 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 191 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1016/j.atherosclerosis.2006.03.016
  • Title of Journal : ATHEROSCLEROSIS
  • Page Numbers: pp.168-174
  • Keywords: slow coronary flow, coronary flow reserve, echocardiography, 2ND-HARMONIC ECHO-DOPPLER, ANGINA-PECTORIS, INTRAVASCULAR ULTRASOUND, SYNDROME-X, ARTERIES, ECHOCARDIOGRAPHY, ATHEROSCLEROSIS, NITROGLYCERIN, DYSFUNCTION, RESISTANCE

Abstract

Background: Slow coronary flow (SCF) in a normal coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. However, previous studies have suggested that microvascular abnormalities and endothelial dysfunction responsible for SCE Accordingly, we hypothesized that SCF phenomenon may be a form, at least early phase, of atherosclerosis that involve both small vessels and epicardial coronary arteries, and therefore we investigated coronary flow reserve (CFR) reflecting coronary microvascular function in patients with SCR