Coronary flow reserve is impaired in patients with slow coronary flow

Erdogan D., ÇALIŞKAN M. , Güllü H., Sezgin A. T. , Yıldırır A., Müderrisoglu İ. H.

ATHEROSCLEROSIS, cilt.191, ss.168-174, 2007 (SCI İndekslerine Giren Dergi) identifier


Background: Slow coronary flow (SCF) in a normal coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. However, previous studies have suggested that microvascular abnormalities and endothelial dysfunction responsible for SCE Accordingly, we hypothesized that SCF phenomenon may be a form, at least early phase, of atherosclerosis that involve both small vessels and epicardial coronary arteries, and therefore we investigated coronary flow reserve (CFR) reflecting coronary microvascular function in patients with SCR