Treatment of gingival recessions associated with noncarious cervical lesions (NCCL) can be a challenging clinical situation for clinicians. Both periodontal and restorative treatment can be necessary for this kind of defect. By using both digitally precise computer-aided design/computer-assisted manufacture (CAD/CAM) procedures and natural inlay (NI) material for restoration of defects before the coronally advanced flap (CAF) surgery, attachment of soft tissues on the root surface can be achieved successfully. Seven nonsmoking patients with NCCL associated with gingival recessions in the maxillary esthetic zone were treated with NI restoration before CAF surgery. All of the included patients needed at least one tooth extraction, and extracted teeth were used for NI restoration for the CAD/CAM milling procedure. After application of the restorative material onto NCCL defects, CAF surgery was performed for root coverage. The primary outcome was increased mean root coverage percentage and clinical attachment gain after a 6-month follow-up period. Successfully restored NCCL defects were covered with CAF, and 91.67% mean root coverage was achieved with a 1.98-mm attachment gain. Additionally, 71.42% of the root surfaces covered completely. Application of NI restoration materials with CAD/CAM techniques can be a promising procedure for the restoration of NCCI. defects before periodontal surgery. This method can achieve a better clinical attachment after root surface coverage.