Enhanced mRNA expression of plasminogen activator inhibitor-1 in livedoid vasculopathy lesions


Agirbasli M. A. , Goktay F., Peker I., Gunes P., Aker F. V. , AKKİPRİK M.

CARDIOVASCULAR THERAPEUTICS, cilt.35, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/1755-5922.12255
  • Dergi Adı: CARDIOVASCULAR THERAPEUTICS

Özet

AimThrombosis and inflammation play an important role in pathophysiology of livedoid vasculopathy (LV). Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of fibrinolysis and is a pivotal modulator in a broad range of biological processes.