Modulation of the immune response to HBV vaccination by hemodialysis membranes

dede f., Yildiz A., ayli d., colak N., ODABAŞ A. R. , akoglu h., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.42, no.4, pp.1069-1075, 2010 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1007/s11255-009-9616-z
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1069-1075

Abstract

Seroconversion response to Hepatitis B virus (HBV) vaccination is limited in uremic patients because of impaired humoral and cellular immune activity. Recent studies show that high-flux (HF) hemodialysis (HD) membranes can improve T cell functions and decrease the proinflammatory cytokine activation more effectively than low-flux (LF) membranes. In regard to HF membranes may have immune modulator effects; we compared the antibody responses to hepatitis B vaccination between HF HD and LF HD membranes.