Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, vol.18, no.6, pp.803-809, 2011 (Journal Indexed in SCI)
Article / Article
Title of Journal :
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
ACE I/D, coronary artery disease, eNOS 3-27, Gln192Arg PON1, MTHFR C677T, multifactor dimensionality reduction, PAI-1 4G/5G, EPISTASIS
Background: Association studies in the Turkish population have investigated the single locus effects of different gene polymorphisms on coronary artery disease (CAD). CAD is a complex polygenic disease that involves complex interactions among multiple genetic and environmental conditions.