JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.30, no.1, pp.126-132, 2016 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF DIABETES AND ITS COMPLICATIONS
Atherosclerosis, Epicardial fat thickness, Flow mediated dilation, Diabetes mellitus type 1, Klotho, PERIPHERAL VASCULAR-DISEASE, INTIMA-MEDIA THICKNESS, ENDOTHELIAL DYSFUNCTION, CLINICAL-APPLICATIONS, CORONARY-ARTERIES, BRACHIAL-ARTERY, EPICARDIAL FAT, ECHOCARDIOGRAPHY, STRAIN, TISSUE
Objective: Klotho deficiency is associated with several metabolic disorders. Two dimensional (2D) longitudinal strain (IS) of left ventricle (LV), carotid artery intima-media thickness (CIMT), flow-mediated dilation (FMD) of brachial artery and epicardial fat thickness (EFT) have been reported to be early predictors of atherosclerosis. We aimed to investigate the relationship between serum Klotho levels and these early predictors of atherosclerosis in patients with type 1 diabetes mellitus (DM).