The Relationship between Glucose Tolerance and Severity of Coronary Artery Disease Using the Gensini Score

NURKALEM Z., HASDEMIR H., ERGELEN M., AKSU H., SAHIN I., ERER B., ...More

ANGIOLOGY, vol.61, no.8, pp.751-755, 2010 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 8
  • Publication Date: 2010
  • Doi Number: 10.1177/0003319710373747
  • Journal Name: ANGIOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.751-755

Abstract

Consecutive patients (n = 235) with coronary ischemia were studied; 69 patients (29%) had diabetes. An oral glucose tolerance test (OGTT) was administered to the 166 patients without diabetes; 76 (46%) had normal glucose tolerance (group I = NGT), 68 (41%) had impaired glucose tolerance ([IGT] group II = IGT), and 22 (13%) had diabetic glucose tolerance (DGT). The DGT patients were added to the known diabetics forming (Group III; n = 91). Multivessel disease was significantly more prevalent in group III; 30 patients (43%) in group I, 32 patients (51%) in group II, and 57 patients (69%) in group III (P = .002). Gensini scores were 43.20 +/- 24.92 in group I, 54.22 +/- 42.61 in group II, and 60.59 +/- 38.21 in group III. (P = .037) The severity of coronary artery disease is related to abnormal glucose tolerance. Patients with IGT could be neglected in terms of interventions focused to improve risk factors.