Serum zonulin level is not elevated in patients with polycystic ovary syndrome without metabolic syndrome

Cetin Z., Kosem A., Can B., Baser O., Catak M., Turhan T., ...More

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.300, no.6, pp.1785-1790, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 300 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.1007/s00404-019-05345-z
  • Journal Name: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1785-1790

Abstract

Aim Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship between PCOS and intestinal permeability has come to an end. Zonulin can change intestinal permeability, and this effect is reversible. We studied the relation between zonulin and the hormonal and metabolic parameters of PCOS.