Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy

Kir, GÖZDE; Arikan, Ea; Seneldir, HATİCE; Ankarali, HANDAN; Oznergiz, S; Olgun, Zc; Yildirim, ASIF

doi:10.1016/j.anndiagpath.2019.151431

Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy

Kir G., Arikan E., Seneldir H., Ankarali H., Oznergiz S., Olgun Z., ...More

ANNALS OF DIAGNOSTIC PATHOLOGY, vol.44, 2020 (Peer-Reviewed Journal)

Publication Type: Article / Article
Volume: 44
Publication Date: 2020
Doi Number: 10.1016/j.anndiagpath.2019.151431
Journal Name: ANNALS OF DIAGNOSTIC PATHOLOGY
Journal Indexes: Science Citation Index Expanded, Scopus, EMBASE, MEDLINE

Abstract

Background: The pre-biopsy (bx) prostate-specific antigen (PSA) level, tumor volume/diameter, degree of extraprostatic extension (EPE), and extent of surgical margin positivity have been shown to be significant prognostic parameters of biochemical recurrence (BCR) after radical prostatectomy. The present study assessed the cut-off values of the pre-bx PSA level, maximum tumor diameter, radial and circumferential distances of EPE, and circumferential length of surgical margin (SM) positivity with regard to BCR.