Determining the cut-off values of tumor diameter, degree of extraprostatic extension, and extent of surgical margin positivity with regard to biochemical recurrence of prostate cancer after radical prostatectomy

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Kir G., Arikan E., Seneldir H., Ankarali H., Oznergiz S., Olgun Z., ...More

ANNALS OF DIAGNOSTIC PATHOLOGY, vol.44, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44
  • Publication Date: 2020
  • Doi Number: 10.1016/j.anndiagpath.2019.151431
  • Journal Indexes: Science Citation Index Expanded, Scopus, EMBASE, MEDLINE


Background: The pre-biopsy (bx) prostate-specific antigen (PSA) level, tumor volume/diameter, degree of extraprostatic extension (EPE), and extent of surgical margin positivity have been shown to be significant prognostic parameters of biochemical recurrence (BCR) after radical prostatectomy. The present study assessed the cut-off values of the pre-bx PSA level, maximum tumor diameter, radial and circumferential distances of EPE, and circumferential length of surgical margin (SM) positivity with regard to BCR.