Metabolic Syndrome: Bridging the Gap from Childhood to Adulthood


Creative Commons License

Agirbasli M. A. , Tanrikulu A. M. , Berenson G. S.

CARDIOVASCULAR THERAPEUTICS, vol.34, no.1, pp.30-36, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 34 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1111/1755-5922.12165
  • Title of Journal : CARDIOVASCULAR THERAPEUTICS
  • Page Numbers: pp.30-36
  • Keywords: Atherosclerosis, Cardiometabolic risk, Children, Lipids disorder, Metabolic syndrome, CARDIOVASCULAR RISK-FACTORS, HIGH-DENSITY-LIPOPROTEIN, INTIMA-MEDIA THICKNESS, 3RD NATIONAL-HEALTH, BODY-MASS INDEX, NUTRITION EXAMINATION SURVEY, SYSTOLIC BLOOD-PRESSURE, HEPATIC LIPASE ACTIVITY, SYNDROME SYNDROME-X, INSULIN-RESISTANCE

Abstract

Childhood and adolescence are particularly vulnerable periods of life to the effects of cardiometabolic risk and later development of atherosclerosis, hypertension, and diabetes mellitus. Developing countries with limited resources suffer most heavily from the consequences of cardiometabolic risk in children and its future implications to the global health burden. A better understanding of mechanisms leading to cardiometabolic risk in early life may lead to more effective prevention and intervention strategies to reduce metabolic stress in children and later disease. Longitudinal tracking studies of cardiometabolic risk in children provide a tremendous global resource to direct prevention strategies for cardiovascular disease. In this review, we will summarize the pathophysiology, existing definitions for cardiometabolic risk components in children. Screening and identifying children and adolescents of high cardiometabolic risk and encouraging them and their families through healthy lifestyle changes should be implemented to as a global public health strategy.