The effects of TNF alpha inhibition on plasma fibrinolytic balance in patients with chronic inflammatory rheumatical disorders


Agirbasli M. A. , Inanc N., Baykan O. A. , Direskeneli H.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.24, no.5, pp.580-583, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2006
  • Title of Journal : CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Page Numbers: pp.580-583

Abstract

Objectives. Recent studies support an inflammatory basis for atherosclerosis. Patients with chronic inflammatory rheumatical disorders are at increased risk for cardiovascular events, and this can be partially attributed to the inhibition of fibrinolytic system. TNF alpha inhibitors such as.infliximab are shown to retard the progression of inflammatory arthritides. In this study, we investigated the effects of infliximab on plasma fibrinolytic parameters.