Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude

Guvenc T. S. , Huseyinoglu N., Ozben S., Kul Ş., Cetin R., Ozen K., ...More

SLEEP AND BREATHING, vol.20, no.1, pp.5-13, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1007/s11325-015-1175-1
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.5-13


Purpose Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.