Effect of nebivolol and metoprolol treatments on serum asymmetric dimethylarginine levels in hypertensive patients with type 2 diabetes mellitus


Oguz A. , Uzunlulu M., Yorulmaz E., Yalcin Y., Hekim N., Fici F.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.7, no.4, pp.383-387, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 4
  • Publication Date: 2007
  • Title of Journal : ANATOLIAN JOURNAL OF CARDIOLOGY
  • Page Numbers: pp.383-387

Abstract

Objective: Elevated asymmetric dimethylarginine (ADMA) levels, an endogenous inhibitor of nitric oxide synthase, are an important cardiovascular risk factor. In patients with diabetes, increased ADMA levels have been reported, which may be associated with endothelial dysfunction. In this study, effect of nebivolol on serum ADMA levels in hypertensive patients with type 2 diabetes have been compared with metoprolol, an another beta-blocker.