The Journal of nutritional biochemistry, vol.98, 2021 (Peer-Reviewed Journal)
Article / Article
The Journal of nutritional biochemistry
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Epilepsy, Microbiota, (neuro)inflammation, Oxidative stress, Probiotic, GUT MICROBIOTA, EPILEPSY, BRAIN, NEUROINFLAMMATION, CHILDREN, INFANTS, DISEASE, MOUSE
Emerging evidence indicates that dysbiosis of gut microbiota plays an important role in epilepsy, although the underlying mechanisms remain unclear due to the complex nature of both microbial composition and pathophysiology of epilepsy. We investigated effects of long-term probiotics supplementation on epileptic seizures, and inflammatory and oxidant/antioxidant biomarkers in a pentylenetetrazole(PTZ)-induced seizure model in rats.