Nephroprotective Efficacy of Sugammadex in Ischemia-Reperfusion Injury: An Experimental Study in a Rat Model

Tercan M., YILMAZ İNAL F., ŞENELDİR H., KOÇOĞLU H.

CUREUS, vol.13, no.6, 2021 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.7759/cureus.15726
  • Journal Name: CUREUS
  • Journal Indexes: Emerging Sources Citation Index
  • Keywords: ischemia-reperfusion, rat models, kidney injury, preconditioning, sugammadex, MYOCARDIAL ISCHEMIA/REPERFUSION-INJURY, KIDNEY

Abstract

Background: It is known that ischemia-reperfusion damage in the kidney is one of the most common causes of acute kidney failure. It is also known that reduced renal damage has a nephroprotective effect by reducing the release of inflammatory and vasoactive peptides that cause tissue damage. Therefore, we think that reperfusion caused by ischemia in kidney damage may be an important focus for clinical research.