Publications & Works

Publication Network

Published journal articles indexed by SCI, SSCI, and AHCI

A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D

Garcia-Rodriguez C., Yan S., Geren I. N. , Knopp K. A. , Dong J., Sun Z., et al.
TOXINS, vol.13, no.9, 2021 (Journal Indexed in SCI) identifier identifier identifier

A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes

Garcia-Rodriguez C., Razai A., Geren I. N. , Lou J., Conrad F., Wen W., et al.
TOXINS, vol.10, no.3, 2018 (Journal Indexed in SCI) identifier identifier identifier

Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B

FAN Y., DONG J., LOU J., WEN W., CONRAD F., Geren I. N. , et al.
TOXINS, vol.7, no.9, pp.3405-3423, 2015 (Journal Indexed in SCI) identifier identifier identifier

Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity

FAN Y., Geren I. N. , DONG J., LOU J., WEN W., CONRAD F., et al.
PLOS ONE, vol.10, no.8, 2015 (Journal Indexed in SCI) identifier identifier identifier

Extraction and inhibition of enzymatic activity of botulinum neurotoxins/B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies

Kalb S. R. , Santana W. I. , Geren I. N. , Garcia-Rodriguez C., Lou J., Smith T. J. , et al.
BMC BIOCHEMISTRY, vol.12, 2011 (Journal Indexed in SCI) Creative Commons License Sustainable Development identifier identifier identifier

Re: oNeutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin by Garcia-Rodriguez et al., PEDS, 2011;24:321331

Garcia-Rodriguez C., GEREN I. N. , Lou J., Conrad F., Forsyth C. , Wen W., et al.
PROTEIN ENGINEERING DESIGN & SELECTION, vol.24, no.9, pp.633-634, 2011 (Journal Indexed in SCI) Creative Commons License identifier identifier identifier

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin

Garcia-Rodriguez C., Geren I. N. , Lou J., Conrad F., Forsyth C., Wen W., et al.
PROTEIN ENGINEERING DESIGN & SELECTION, vol.24, no.3, pp.321-331, 2011 (Journal Indexed in SCI) Creative Commons License Sustainable Development identifier identifier identifier

Recombinant Anthrax Toxin Receptor-Fc Fusion Proteins Produced in Plants Protect Rabbits against Inhalational Anthrax

Wycoff K. L. , Belle A., Deppe D., Schaefer L., Maclean J. M. , Haase S., et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol.55, no.1, pp.132-139, 2011 (Journal Indexed in SCI) Creative Commons License Sustainable Development identifier identifier identifier

Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating

Lou J., Geren I. N. , Garcia-Rodriguez C., Forsyth C. M. , Wen W., Knopp K., et al.
PROTEIN ENGINEERING DESIGN & SELECTION, vol.23, no.4, pp.311-319, 2010 (Journal Indexed in SCI) Creative Commons License identifier identifier identifier

Extraction and Inhibition of Enzymatic Activity of Botulinum Neurotoxins/A1, /A2, and /A3 by a Panel of Monoclonal Anti-BoNT/A Antibodies

Kalb S. R. , Lou J., Garcia-Rodriguez C., Geren I. N. , Smith T. J. , Moura H., et al.
PLOS ONE, vol.4, no.4, 2009 (Journal Indexed in SCI) Sustainable Development identifier identifier identifier

The use of Endopep-MS to detect multiple subtypes of botulinum neurotoxins A, B, E, and F

Kalb S. R. , Smith T. J. , Moura H., Hill K., Lou J., Geren I. N. , et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, vol.278, pp.101-108, 2008 (Journal Indexed in SCI) Sustainable Development identifier identifier

Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy

Fischer A., Garcia-Rodriguez C., Geren I. N. , Lou J., Marks J. D. , Nakagawa T., et al.
JOURNAL OF BIOLOGICAL CHEMISTRY, vol.283, no.7, pp.3997-4003, 2008 (Journal Indexed in SCI) Creative Commons License identifier identifier identifier

Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display

Levy R., Forsyth C. M. , LaPorte S. L. , Geren I. N. , Smith L. A. , Marks J. D.
JOURNAL OF MOLECULAR BIOLOGY, vol.365, no.1, pp.196-210, 2007 (Journal Indexed in SCI) Creative Commons License Sustainable Development identifier identifier identifier

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin

GARCIA-RODRIGUEZ C., LEVY R., ARNDT J. W. , FORSYTH C. M. , RAZAI A., LOU J., et al.
NATURE BIOTECHNOLOGY, vol.25, no.1, pp.107-116, 2007 (Journal Indexed in SCI) identifier identifier identifier

Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralizaiion

Smith T., Lou J., Geren I. N. , Forsyth C., Tsai R., LaPorte S., et al.
INFECTION AND IMMUNITY, vol.73, no.9, pp.5450-5457, 2005 (Journal Indexed in SCI) Creative Commons License Sustainable Development identifier identifier identifier

Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A

Razai A., GARCIA-RODRIGUEZ C., Lou J., Geren I. N. , FORSYTH C., ROBLES Y., et al.
JOURNAL OF MOLECULAR BIOLOGY, vol.351, no.1, pp.158-169, 2005 (Journal Indexed in SCI) identifier identifier identifier

BETA-THALASSEMIA IN IRAN - A HIGH-INCIDENCE OF THE NONSENSE CODON-39 MUTATION ON THE ISLAND OF QUESHM

Naloii M., Moazami N., Ferhangi S., Atalay A., GEREN I. N. , Akar L., et al.
HEMOGLOBIN, vol.18, no.6, pp.449-453, 1994 (Journal Indexed in SCI) identifier

Refereed Congress / Symposium Publications in Proceedings

Human monoclonal antibodies binding botulinum neurotoxin types C, D, and mosaic neurotoxins C-D and D-C

Garcia C., YAN S., Geren I. N. , Lou J., Wen W., Conrad F., et al.
7th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins (TOXINS), Santa Fe, Argentina, 2 - 05 October 2011, vol.68, pp.86-87 identifier

Recombinant monoclonal-antibody-based antitoxins for treatment of types A, B, and E botulism

TOMIC M., Garcia C., Lou J., Geren I. N. , MENG Q., Conrad F., et al.
7th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins (TOXINS), Santa Fe, Argentina, 2 - 05 October 2011, vol.68, pp.99-100 identifier

Recombinant antibody potently neutralizes types A, B, and E botulinum neurotoxins by a clearancedriven mechanism

MARKS J., Garcia C., Geren I. N. , LOU J., FORSYTH C. M. , FRASER C., et al.
6th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, Baveno, Italy, 12 - 15 June 2008, vol.51, pp.50 identifier

Affinity and specificity maturation of Human antibodies against Botulinum neurotoxin types A and B via yeast Mating.

Lou J., GEREN I. N. , Consuelo G., Wen W., Knopp K., Forsyth C. M. , et al.
The 44th annual Interagency Botulism Research Coordinating Committee (IBRCC) Meeting, United States Of America, 01 October 2007

Protection Using Equine AB Fab2 Antitoxin Against BoNT A and BoNT B Subtypes

Brown J., Forsyth C., Smith T., Lou J., GEREN I. N. , Consuelo G., et al.
The 43rd Interagency Botulism Research Coordinating Committee (IBRCC) conference in Washington, United States Of America, 01 November 2006

Engineered recombinant antibody potently neutralizes type A botulinum neurotoxins by a clearance driven mechanism

GEREN I. N. , Jianlong L., Consuelo G., Forsyth C. M. , Levy R., Wen W., et al.
The 43rd Interagency Botulism Research Coordinating Committee (IBRCC) conference in Washington, United States Of America, 01 November 2006

Engineered Recombinant Antibody Potently Neutralizes Type B Botulinum Neurotoxins.

Lou J., GEREN I. N. , Consuelo G., Forsyth C. M. , Wen W., Knopp K., et al.
The 43rd Interagency Botulism Research Coordinating Committee (IBRCC) conference in Washington, United States Of America, 01 November 2006

Affinity and Specificity Maturation of Human Antibody against Botulinum Neurotoxins via Molecular Evolution and Yeast Mating

Lou J., GEREN I. N. , Garcia-Rodriguez C., Forsyth C., Robles Y., Knopp K., et al.
Society of Chinese Bioscientists in America The 11th International Symposium., United States Of America, 01 July 2006, vol.10, no.13

Recombinant Engineered Antibody Potently Neutralizes Known and Novel A type Botulinum Neurotoxins.

Lou J., GEREN I. N. , Garcia C., Razai A., Forsyth C., Knopp K., et al.
SINO-US Symposium on Medicine in 21st Century, United States Of America, 01 August 2005

Affinity and Specificity Maturation of Fab Antibody Fragments against Botulinum Neurotoxin by Yeast Mating

GEREN I. N. , Lou J., Robles Y., Knopp K., Wen W., Tsai R., et al.
SINO-US Symposium on Medicine in 21st Century, United States Of America, 01 August 2005

High-Affinity Antibodies Which Neutralize Botulinum Neurotoxin From Libraries of Single Chain Displayed on Yeast

GEREN I. N. , Jianlong L., Razai A., Tasai R., Miller J., Garcia C., et al.
Antibody Engineering, Forging the Future of Antibody Therapeutics, United States Of America, 01 December 2003

Engineering high affinity and cross reactive botulinum antibodies using yeast display.

Consuelo G., Jianlong L., GEREN I. N. , Razai A., Tsai R., Miller J., et al.
Antibody Engineering, Forging the Future of Antibody Therapeutics, United States Of America, 01 December 2003

Selection of High affinity human antibodies against botulinum neurotoxin from a large Fab libraries created by yeast mating

Jianlong L., Feldhaus M., GEREN I. N. , Tsai R., Shigel R., Smith T., et al.
Antibody Engineering, Forging the Future of Antibody Therapeutics, United States Of America, 01 December 2003

Rekombinant DNA teknolojisi ile Rekombinant bir Antijene Karsi Antikor Üretimi

GEREN I. N.
Marmara Üniversitesi, Sağlık Bilimleri Enstitüsü Mezuniyet Töreni ve Doktora Günleri IV, İstanbul, Turkey, 01 November 2000

TRANSFORMATION OF STREPTOCOCCUS-THERMOPHILUS WITH PLASMID DNA BY ELECTROPORATION

GUNDUZ U., GEREN I. N. , EREN E., YILDIZ F., GUNDUZ G.
NATO ADVANCED STUDY INST ON RECENT ADVANCES IN INDUSTRIAL APPLICATIONS OF BIOTECHNOLOGY, KUSADASI, Turkey, 16 - 27 September 1991, vol.210, pp.361-366 identifier

Books & Book Chapters

Antibody Engineering Protocols PART I Construction of Recombinant Antibody Libraries

Geren I. N.
Nobel Yayınevi, Ankara, 2021 Sustainable Development

Transformation of Streptococcus Thermophilus with plasmid DNA by electroporation

Gündüz U., GEREN I. N. , Eren E., Yıldız F., Gündüz G.
in: Recent Advances in Biotechnology (NATO Science Series E), Fazilet Vardar-Sukan, S. Suha Sukan, Editor, Kluwer Aacdemic Publishers, -, pp.361-366, 1992